Trauma surgeon-performed peripheral arterial repairs are associated with equivalent outcomes when compared with vascular surgeons.

BACKGROUND: Civilian extremity trauma with vascular injury carries a significant risk of morbidity, limb loss, and mortality. We aim to describe the trends in extremity vascular injury repair and compare outcomes between trauma and vascular surgeons. METHODS: We performed a single-center retrospective review of patients 18 years or older with extremity vascular injury requiring surgical intervention between January 2009 and December 2019. Demographics, injury characteristics, operative course, and hospital course were analyzed. Descriptive statistics were used to examine management trends, and outcomes were compared for arterial repairs. Multivariate regression was used to evaluate surgeon specialty as a predictor of complications, readmission, vascular outcomes, and mortality. RESULTS: A total of 231 patients met our inclusion criteria; 80% were male with a median age of 29 years. The femoral vessels were most commonly injured (39.4%), followed by the popliteal vessels (26.8%). Trauma surgeons performed the majority of femoral artery repairs (82%), while vascular surgeons repaired the majority of popliteal artery injuries (84%). Both had a similar share of brachial artery repairs (36% vs. 39%, respectively). There were no differences in complications, readmission, vascular outcomes, and mortality. Median time from arrival to operating room was significantly shorter for trauma surgeons. There was a significant downward trend between 2009 and 2017 in the proportion of total and femoral vascular procedures performed by trauma surgeons. On multivariate regression, surgical specialty was not a significant predictor of need for vascular reintervention, prophylactic or delayed fasciotomies, postoperative complications, or readmissions. CONCLUSION: Traumas surgeons arrived quicker to the operating and had no difference in short-term clinical outcomes of brachial and femoral artery repairs compared with patients treated by vascular surgeons. Over the last decade, there has been a significant decline in the number of open vascular repairs done by trauma surgeons. LEVEL OF EVIDENCE: Therapeutic/Care Management, Level IV.

The anterolateral thigh flap for groin and lower abdominal defects: a better alternative to the rectus abdominis flap.

BACKGROUND: Historically, the mainstay of soft-tissue reconstruction in the groin and lower abdomen has been the anatomically consistent, easily elevated rectus abdominis flap, with variations. Insetting the rectus abdominis flap here requires creating an abdominal wall defect through which to pass the pedicle, which raises the risk of donor-site morbidity. Although popular as a free flap, the anterolateral thigh flap as a pedicled flap in the groin and lower abdomen has not been directly compared with the rectus abdominis flap. METHODS: Retrospective record review was conducted on 39 patients who underwent groin or lower abdominal wall reconstruction (30 anterolateral thigh flap and 10 rectus abdominis flap procedures) to address oncologic defects, lymphadenectomy, and complications of vascular bypass. Patient demographics and comorbidities, flap characteristics, postoperative complications, and time to heal were compared. RESULTS: All patients in both the anterolateral thigh and rectus abdominis flap groups healed at the flap recipient sites. Despite similar patient characteristics, wound cause was different between the groups, with more infected wounds being treated in the anterolateral thigh flap group. Early postoperative complication rates were similar in both groups. Anterolateral thigh flap patients had shorter time to healing, with lower rates of delayed (>30 days) postoperative complications compared with rectus abdominis flap patients. Six rectus abdominis flap patients developed delayed abdominal incisional hernias. No donor- or recipient-site complications were encountered in anterolateral thigh flap patients after 90 days. CONCLUSION: The pedicled anterolateral thigh flap is the preferred choice for reconstruction of wounds in the groin and lower abdomen.

Sacral neural crest-derived cells enter the aganglionic colon of Ednrb-/- mice along extrinsic nerve fibers.

Both vagal and sacral neural crest cells contribute to the enteric nervous system in the hindgut. Because it is difficult to visualize sacral crest cells independently of vagal crest, the nature and extent of the sacral crest contribution to the enteric nervous system are not well established in rodents. To overcome this problem we generated mice in which only the fluorescent protein-labeled sacral crest are present in the terminal colon. We found that sacral crest cells were associated with extrinsic nerve fibers. We investigated the source, time of appearance, and characteristics of the extrinsic nerve fibers found in the aganglionic colon. We observed that the pelvic ganglion neurons contributed a number of extrinsic fibers that travel within the hindgut between circular and longitudinal muscles and within the submucosa and serosa. Sacral crest-derived cells along these fibers diminished in number from fetal to postnatal stages. A small number of sacral crest-derived cells were found between the muscle layers and expressed the neuronal marker Hu. We conclude that sacral crest cells enter the hindgut by advancing on extrinsic fibers and, in aganglionic preparations, they form a small number of neurons at sites normally occupied by myenteric ganglia. We also examined the colons of ganglionated preparations and found sacral crest-derived cells associated with both extrinsic nerve fibers and nascent ganglia. Extrinsic nerve fibers serve as a route of entry for both rodent and avian sacral crest into the hindgut.